Customized Services

Business Solutions :

Supporting global pharmaceutical companies through the research, development and production of complex RSM’s and API from early stage clinical trials through commercialization.

Our research institute offers extensive research capabilities

    ● 80 highly experienced scientists providing process R&D route design to full CMC support and chemical synthesis solutions
    ● Technology expertise in
         ○ Chiral synthesis
         ○ Heterocyclic chemistry
         ○ Continuous flow chemistry
         ○ Photochemistry
    ● Comprehensive Analytical Capabilities
         ○ HPLC, LCMS, HRMS, NMR, RM, ICP-MS, TGA, Marvin granulometer, ICS, etc.
    ● Safety & Risk Assessment
         ○ Mettler DCS, Mettler RC 1e, THT ARC

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Massive production Plant

  1.  10 chemical synthesis workshops
  2.  1 hydrogenation workshop
  3.  5 API GMP workshops
  4.  432 reactors with a total volume of 1,424.8 m2.
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Environmental Responsibility

State-of-the-art EH&S Infrastructure
  · Standalone 500 mt/d wastewater treatment facility
  · RTO including 2 gas powered waste incinerators
  · On-Site Liquid Waste Incineration (VR), DCS & IS

CDMO / CMO of small molecular chemical API and intermediates

The CDMO project of the company is led by Dr. George Shi, a national high-level talent, responsible for high value-added projects with high technical requirements and difficult process development. After years of accumulation, the company has the ability to undertake various CDMO projects with high technology content, and the main techniques and capabilities are as follows:

  1. Hydrogenation reaction: hydrogenation reactors (including Hastelloy alloy) with a capacity of 300 to 6,000 liters and a pressure of 100 ATM;
  2. Ammoniation reaction: maximum of 10,000 liters of liquid ammonia ammoniation reactor, liquid ammonia storage license is issued.;
  3. Nitrification, diazotization, azide and other reactions;
  4. Ultra-low temperature reaction: maximum below -80℃, continuously controlled is below -60℃;
  5. Metal catalytic reaction: highly active metal catalytic reaction technology;
  6. Molecular distillation technology and equipment;
  7. Chiral split technology;
  8. Continuous flow microchannel green chemistry technology;
  9. Photochemical reaction technology;
  10. Safety control technology of ultra-high temperature reaction : up to 280℃;
  11. Safety evaluation technology of chemical process : DSC, RC1, ARC and other safety evaluation facilities and technicians.
Our Advantages

Synthetic pharmaceutical R&D and manufacturing
Production capability: temperature from -78 to 250 ℃, pressure up to 100 atm, Grignard reaction, Azide reaction, Amination reaction, Borane chemistry, Nitration, Flow chemistry, Photo chemistry, NaCIO-TEMPO oxidation, Peptide liquid / solid phase synthesis)
Professional technology transfer
GMP & ICHQ 7 guideline
Cost control Management